Moving Science Podcast

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Moving Science - A Roche Podcast for the MS Community

Introducing the first series of Moving Science on the main theme of How to best manage & maintain health in MS.

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This podcast is for everyone who wants to join healthcare professionals, people with MS and their carers as they delve into unmet needs in current MS Care, opportunities to address them through innovation and envisioning a better future with a more personalized and equitable MS Care for people with MS across the globe.

Designed for your convenience, our podcast format allows you to seamlessly incorporate episodes into your daily routine—whether you're commuting to work, cooking, doing sports or simply unwinding with a soothing cup of tea.

Get started by listening to the first episodes through the links below.



If you would like to share your thoughts or suggest specific topics, please send an email anytime to ms.innovationchallenge@roche.com.

 

Episode 1

Moving Science: how it all started and where it is going

Join us on an immersive journey into the fascinating world of innovation, science, and their profound impact on medical care with our inaugural series on "How to best manage & maintain health in MS."

In the first episode, our esteemed host, Prof. Gavin Giovannoni from the Queen Mary University of London and Blizard Institute, talks about the main podcast theme and dives deeper into motivations behind this initiative. Learn more about the diverse audiences we aim to connect with, and get a sneak peek into our next episode, featuring our very first guest speaker.

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Episode 2

MS care: Integrating advanced therapies and lifestyle factors in a holistic management

Explore the innovative strategies transforming MS care in our second episode, where we delve into the principles of person-centered and holistic management. This approach combines prompt treatment with effective disease-modifying therapies and the adoption of a "brain-healthy lifestyle" from the time of diagnosis.

In this episode, Prof. Gavin Giovannoni from Queen Mary University of London and Blizard Institute, along with Dr. Agne Straukiene from Torbay and South Devon NHS Foundation Trust and the University of Plymouth, discuss the critical importance of brain health. They examine various lifestyle behaviors that can be integrated into daily routines to support life-long brain health in people with MS. Additionally, they explore the benefits of a multidisciplinary, collaborative approach in clinical practice.

The discussion also emphasizes the pressing need for further research to advance diagnostic and therapeutic strategies, providing more evidence to support and prove the value of holistic care. Join us to gain valuable insights into how these innovative approaches can significantly improve MS management and patient outcomes.
For those interested in gaining more insights on this subject, the following recent research article is recommended to be read:

Giovannoni G, Ford HL, Schmierer K, Middleton R, Stennett AM, Pomeroy I, Fisniku L, Scalfari A, Bannon C, Stross R, Hughes S, Williams A, Josephs S, Peel C, Straukiene A.

MS care: integrating advanced therapies and holistic management. Front Neurol. 2024 Jan 30;14:1286122. doi: 10.3389/fneur.2023.1286122. PMID: 38351950; PMCID: PMC10862341.

 

 

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Episode 3

What is the promise of Artificial Intelligence and Real-World Data in MS?

Imagine a world where MS management is no longer a one-size-fits-all approach, but rather a personalized and tailored experience. In this third episode, we unveil how the integration of advanced technologies is paving the way for a new era of MS care.

According to Prof. Dr. Gavin Giovannoni and PD Dr. Benjamin Friedrich, the importance of listening to the patient and understanding their needs is fundamental. Benjamin Friedrich emphasizes the value of patient feedback and the opportunity for new technology, stating: “In my personal experience, patients have often been very good at telling you when something has changed. You can't measure it objectively, but they are adamant and say, 'No, something has changed. Something is different.' I think technology will really aid us in identifying and tracking those very subtle changes over time."

In this episode, Prof. Dr. Gavin Giovannoni from the Queen Mary University of London and Blizard Institute, along with PD Dr. Benjamin Friedrich, Co-Founder & Chief Medical Officer of Temedica and board certified neuroradiologist, discuss the following key topics:

  • Current MS Research Challenges: Understanding the pathophysiology of MS; addressing the complexities in diagnosis and treatment taking into account the heterogeneity of the disease.
  • Unlocking the power of RWD: Harnessing data from diverse sources like electronic health records and mobile devices to drive comprehensive insights and ultimately optimize treatment approaches.
  • Impact of AI: Utilizing AI for predictive analytics in disease progression and treatment responses, improving imaging and diagnostics for earlier detection, and exploring future trends in advanced predictive models and real-time patient monitoring.
  • Ethical Considerations: Ensuring data privacy and security, addressing biases in AI algorithms, and emphasizing the augmentation of clinician expertise with technology.

Explore the episode now to discover how AI and RWD are reshaping the future of MS care.

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Episode 4

Urgency of Change in MS Care 

"What really drives me in this, is the concept of hope because the further we go into our innovation journey with MS, the greater are our opportunities to offer true hope to people and their families with MS." - Amy Perrin Ross

Hosted by the esteemed Prof. Dr. Gavin Giovannoni from the Queen Mary University of London, this episode features an incredible panel of experts, including 

  • Dr. Leorah Freeman, neurologist and Medical Director of the MS and Neuroimmunology Center at Dell Medical School, The University of Texas, Austin 
  • Kasey Minnis, Executive Director of the Multiple Sclerosis Foundation, Fort Lauderdale, Florida, and
  • Amy Perrin Ross, Advanced practice MS nurse & Program Coordinator at the Loyola University Medical Center, Chicago, Illinois, and past President of the International Organization of MS Nurses.

In this episode, titled “Urgency of Change in MS Care,” you can expect an enriching conversation that promises to inspire and empower all who seek a deeper understanding of MS management and patient well-being. 

Part 1 of the discussion delves into the significant unmet needs of people with MS and their carers, shedding light on the challenges clinicians face in their medical routines. Furthermore, our panelists share their personal commitments to improving the lives of people with MS and explore innovative solutions that are shaping the future of MS care. Tune in and be part of the movement driving positive change in MS care.

 

 

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Embark on Part 2 of our thrilling journey where innovation meets medical practice to tackle unmet needs. Our expert panelists will reveal the transformative power of cutting-edge technologies and biomarkers, enabling a deeper understanding of each patient's unique disease journey.

But we don't stop there—our podcast takes you into the future of MS care, imagining a world where healthcare is streamlined and accessible for everyone with MS, no matter where they are.

Are you ready to join this groundbreaking adventure? Tune in to our podcast and dive into the ever-evolving world of MS care!

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Episode 5

Part 1: Advancing Health Equity in MS Care

Welcome to Part One of Episode 5 of the Moving Science Podcast, where we focus on advancing health equity in MS care. This episode is hosted by Quita Highsmith, Vice President and Chief Diversity Officer at Genentech, and features Dr. Mitzi Williams, neurologist and top subject matter expert in Neurology, Multiple Sclerosis, and Health Disparities.

Dr. Williams shares profound insights into her career journey and the driving forces behind her dedication to neurology. Furthermore, the below critical topics are discussed:

  • Commitment to Health Equity: Discussing Dr. Williams’ dedication to improving global MS management for all people with MS
  • Disparities in MS Care: Exploring existing disparities based on various causes such as race, ethnicity, socioeconomic status, and geography and talking about unmet needs
  • MS Innovation Challenge: Developed by Roche and Genentech, this initiative aims to drive real change through early detection of MS, enabling early and efficient treatment, and improving monitoring and prediction of the disease's impact. We discuss how this can help enhance care for people with MS and address existing disparities.
  • Future of MS Care & Outlook: Dr. Williams shares her excitement about future advancements in MS care. Quita Highsmith provides a sneak peek into Part Two, where both speakers will explore much needed diversity and inclusion in MS research.

 

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Part 2: Advancing Health Equity in MS Care

 

Join us for Part Two of Episode 5 on advancing health equity in MS care with the esteemed Dr. Mitzi Williams. Hosted by Quita Highsmith, this episode continues the insightful discussion on addressing and preventing disparities in MS through innovation and inclusive research.

In this episode, we focus on:

  • Innovation in MS: How innovation can prevent disparities for people with MS
  • Diversity and Inclusion in MS Research: How Roche and Genentech are Advancing Inclusive Research and the groundbreaking CHIMES study
  • MS Innovation Challenge: How Roche and Genentech’s MS Innovation Challenge is challenging the status quo in the MS space
  • Access to Innovative Therapies: The importance of access to research and care for underserved populations

We will explore what's missing in the MS space and discuss actionable steps to drive real change. Together, we can work towards increasing diversity and inclusion in MS research and management. Tune In and be part of the change.

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Episode 6: Navigating Artificial Intelligence-led Education in Healthcare

Host: Dr. Agne Straukiene

Speaker: Prof. Dr. Heinz Wiendl
 

Part 1: Transforming Healthcare Education through Artificial Intelligence

In the first part of the podcast, Dr. Agne Straukiene and Prof. Dr. Heinz Wiendl explore the revolutionary impact of Artificial Intelligence (AI) on healthcare education with a focus on Multiple Sclerosis (MS). Together, they discuss how innovative AI tools are reshaping learning processes and information management for patients and healthcare professionals, facilitating a better understanding of modern medicine and enhancing decision-making in healthcare.

 

 

 

 

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Part 2: Emerging AI Tools and Ethical Considerations

The discussion continues with a deeper dive into cutting-edge AI tools that are emerging in the healthcare sector. In this segment, our speakers present example cases that highlight the practical applications of these tools in medical practice. Furthermore, they present a view of the current landscape with special emphasis on Neurology and MS, the future potential of AI-led education in healthcare, as well as touching on important regulations and ethical considerations.

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Episode 7: What is the clinical value of Neurofilament light (NfL) in MS Care today and in the future?
Host: Prof. Dr. Gavin Giovannoni
Speakers: Prof. Dr. Tanuja Chitnis, Dr. Sharmilee Gnanapavan, Dr. Ahmed Obeidat

Part 1: Join Prof. Dr. Gavin Giovannoni and a distinguished panel of international experts – Prof. Dr. Tanuja Chitnis, Dr. Sharmilee Gnanapavan, and Dr. Ahmed Obeidat – for a highly educational and thought-provoking podcast. Rich with expert insights and engaging discussions, it offers a comprehensive exploration of the clinical value of NfL in current MS care and the evolving role of fluid biomarkers in the future of medical practice.

The panel shares state-of-the-art knowledge about NfL and discusses experiences from the daily clinical routine, highlighting how NfL provides an additional window for more frequent monitoring of disease activity in people with MS. They also explain how combining NfL with other fluid biomarkers, clinical outcomes, and MRI findings can enhance patient monitoring and improve prognostication.

Tune in to enhance your understanding and stay at the forefront of MS care advancements.

 

 

 

 

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Part 2: Join our continued discussion with Prof. Dr. Gavin Giovannoni and the panel as they delve deeper into current and future applications of NfL and other blood-based biomarkers.

The panel explores key aspects of integrating NfL into medical practice, ranging from consistent assay methods for longitudinal data interpretation to accounting for comorbidities. They also address challenges when interpreting discrepancies and discuss access issues in different healthcare systems.

Additionally, the experts examine the combination of NfL with other biomarkers such as GFAP and Neurofilament heavy chain in multivariate panels, assessing how these combinations can enhance diagnostic and prognostic value across different sub-populations, including pediatric patients and those with progressive courses of MS.

Looking to the future, they imagine a world where people with MS can monitor their biomarker levels at home and explore the potential of blood-based biomarkers for screening and serial monitoring of individuals at risk for various neurological conditions.

Immerse yourself in the recent developments and understand the emerging impact of fluid biomarkers in healthcare.

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